Dr. Simone Lemeer
| Position: |
Group Leader Mass Spectrometry |
 |
| Room: |
007 |
| Category: |
Scientific Staff |
| Phone: |
+49 - (0)8161 - 714369 |
| Email: |
|
Publications
Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer.
Mol Cell Proteomics. 2011 Sep 28. [Epub ahead of print] DOI: -
Tyrosine phosphorylation profiling in FGF-2 stimulated human embryonic stem cells.
PLoS One. 2011 Mar 17;6(3):e17538. DOI: -
| Ding VM | Boersema PJ | Foong LY | Preisinger C | Koh G | Natarajan S | Lee DY | Boekhorst J | Snel B | Lemeer S | Heck AJ | Choo A | Source | Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore, Singapore. |
| Online reference |
Phosphorylation site localization in peptides by MALDI MS/MS and the Mascot Delta Score.
Anal Bioanal Chem. 2012 Jan;402(1):249-60. Epub 2011 Oct 25. DOI: -
Phosphotyrosine mediated protein interactions of the discoidin domain receptor 1.
J Proteomics. 2011 Oct 26. [Epub ahead of print] DOI: -
| Lemeer S | Bluwstein A | Wu Z | Leberfinger J | Müller K | Kramer K | Kuster B | Source | Chair of Proteomics and Bioanalytics, Technische Universität München, Emil Erlenmeyer Forum 5, 85354 Freising, Germany. |
| Online reference |
Confident phosphorylation site localization using the Mascot Delta Score.
Mol Cell Proteomics. 2010 Nov 6. [Epub ahead of print] DOI: -
High-resolution mapping of prostaglandin E2-dependent signaling networks identifies a constitutively active PKA signaling node in CD8+CD45RO+ T cells.
Blood. 2010 Sep 30;116(13):2253-65. Epub 2010 Jun 17. DOI: -
| Oberprieler NG | Lemeer S | Kalland ME | Torgersen KM | Heck AJ | Taskén K | Source | The Biotechnology Centre of Oslo and Centre for Molecular Medicine, Nordic EMBL Partnership, University of Oslo, Blindern, Oslo, Norway. |
| Online reference |
Confident phosphorylation site localization using the Mascot Delta Score.
Mol Cell Proteomics. 2011 Feb;10(2):M110.003830. Epub 2010 Nov 6. DOI: -
Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics.
Nat Protoc. 2009 March;4(4):484-94. DOI: -
In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling.
Mol Cell Proteomics. 2010 Jan;9(1):84-99. Epub 2009 Sep 21. DOI: -
| Lemeer S | Boersema PJ | Foong LY | Ding VM | van Breukelen B | Philp R | Boekhorst J | Snel B | den Hertog J | Choo AB | Heck AJ |
| Online reference |
The phosphoproteomics data explosion.
Curr Opin Chem Biol. 2009 Oct;13(4):414-20. Epub 2009 Jul 19. DOI: -
A versatile peptide pI calculator for phosphorylated and N-terminal acetylated peptides experimentally tested using peptide isoelectric focusing.
Proteomics. 2008 Dec;8(23-24):4898-906. DOI: -
Online automated in vivo zebrafish phosphoproteomics: from large-scale analysis down to a single embryo.
J Proteome Res. 2008 Apr;7(4):1555-64. Epub 2008 Feb 29. DOI: -
Chip-Based Enrichment and NanoLC-MS/MS Analysis of Phosphopeptides from Whole Lysates.
J Proteome Res. 2008 Apr;7(4):1565-71. Epub 2008 Feb 29. DOI: -
Comparative phosphoproteomics of zebrafish Fyn/Yes morpholino knockdown embryos.
Mol Cell Proteomics. 2008 Nov;7(11):2176-87. Epub 2008 Jun 11. DOI: -
Protein-tyrosine kinase activity profiling in knock down zebrafish embryos.
PLoS One. 2007 Jul 4;2(7):e581. DOI: -
Endogenous phosphotyrosine signaling in zebrafish embryos.
Mol Cell Proteomics. 2007 Dec;6(12):2088-99. Epub 2007 Aug 14. DOI: -
Reversible oxidation of the membrane distal domain of receptor PTPalpha is mediated by a cyclic sulfenamide.
Biochemistry. 2007 Jan 23;46(3):709-19. DOI: -
Differential oxidation of protein-tyrosine phosphatases.
J Biol Chem. 2005 Mar 18;280(11):10298-304. Epub 2004 Dec 28. DOI: -
| Groen A | Lemeer S | van der Wijk T | Overvoorde J | Heck AJ | Ostman A | Barford D | Slijper M | den Hertog J |
| Online reference |
The AP-2 complex is excluded from the dynamic population of plasma membrane-associated clathrin.
J Biol Chem. 2003 Nov 28;278(48):47357-60. Epub 2003 Oct 6. DOI: -
A ubiquitin-interacting motif (UIM) is essential for Eps15 and Eps15R ubiquitination.
J Biol Chem. 2002 Aug 23;277(34):30746-53. Epub 2002 Jun 18. DOI: -
A protocol on the use of titanium dioxide chromatography for phosphoproteomics.
Methods Mol Biol. 2011;753:215-28. DOI: -
| Pinkse MW | Lemeer S | Heck AJ | Source | Department of Biotechnology, Technical University of Delft, Delft, 2628, BC, The Netherlands. m.w.h.pinkse@tudelft.nl |
| Online reference |
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Chair of Proteomics and Bioanalytics
NEWS
15 April 2012
Glyco-TMTs -- novel tools for glyco-proteomics
more
13 October 2011
TUM and Oxford scientists team up for the identification of novel drug targets and biomarkers in head & neck cancer.
more
25 April 2011
Chair of proteomics acquires 2.5 M€ large scale equipment grant for interdisciplinary research
more
29 March 2011
New O-GlcNAc research paper in JASMS
more
26 November 2010
Life science teaching award for Bernhard Kuster
more
News archive
