Prof. Dr. Bernhard Küster
| Position: |
Head |
 |
| Room: |
105 |
| Category: |
Scientific Staff |
| Phone: |
+49 - (0)8161 - 715696 |
| Email: |
|
Publications
Systematic identification of the HSP90 regulated proteome.
Mol Cell Proteomics. 2012 Feb 14. [Epub ahead of print] DOI: -
Carbonyl-reactive tandem mass tags for the proteome-wide quantification of N-linked glycans.
Anal Chem. 2012 Mar 28. [Epub ahead of print] DOI: -
Lactocepin secreted by lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines.
Cell Host Microbe. 2012 Apr 19;11(4):387-96. DOI: -
| von Schillde MA | Hörmannsperger G | Weiher M | Alpert CA | Hahne H | Bäuerl C | van Huynegem K | Steidler L | Hrncir T | Pérez-Martínez G | Kuster B | Haller D | Source | Chair for Biofunctionality, ZIEL Research Center for Nutrition and Food Science, CDD Center for Diet and Disease, Technische Universität München, Gregor-Mendel-Straße 2, 85350 Freising-Weihenstephan, Germany. |
| Online reference |
Ultra-high intra-spectrum mass accuracy enables unambiguous identification of fragment reporter ions in isobaric multiplexed quantitative proteomics.
Proteomics. 2012 May;12(9):1328-32. doi: 10.1002/pmic.201100622. DOI: -
Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer.
Mol Cell Proteomics. 2011 Sep 28. [Epub ahead of print] DOI: -
Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation.
Gastroenterology. 2011 May 26. [Epub ahead of print] DOI: -
| Steck N | Hoffmann M | Sava IG | Kim SC | Hahne H | Tonkonogy SL | Mair K | Krueger D | Pruteanu M | Shanahan F | Vogelmann R | Schemann M | Kuster B | Sartor RB | Haller D |
| Online reference |
A Novel Two-Stage Tandem Mass Spectrometry Approach and Scoring Scheme for the Identification of O-GlcNAc Modified Peptides.
J Am Soc Mass Spectrom. 2011 May;22(5):931-42. Epub 2011 Mar 26. DOI: -
Phosphorylation site localization in peptides by MALDI MS/MS and the Mascot Delta Score.
Anal Bioanal Chem. 2012 Jan;402(1):249-60. Epub 2011 Oct 25. DOI: -
Phosphotyrosine mediated protein interactions of the discoidin domain receptor 1.
J Proteomics. 2011 Oct 26. [Epub ahead of print] DOI: -
| Lemeer S | Bluwstein A | Wu Z | Leberfinger J | Müller K | Kramer K | Kuster B | Source | Chair of Proteomics and Bioanalytics, Technische Universität München, Emil Erlenmeyer Forum 5, 85354 Freising, Germany. |
| Online reference |
Confident phosphorylation site localization using the Mascot Delta Score.
Mol Cell Proteomics. 2010 Nov 6. [Epub ahead of print] DOI: -
Proteomics: a pragmatic perspective.
Nat Biotechnol. 2010 Jul;28(7):695-709. Epub 2010 Jul 9. DOI: -
Confident phosphorylation site localization using the Mascot Delta Score.
Mol Cell Proteomics. 2011 Feb;10(2):M110.003830. Epub 2010 Nov 6. DOI: -
Affinity purification of proteins binding to kinase inhibitors immobilized on self-assembling monolayers.
Methods Mol Biol. 2012;795:149-60. DOI: -
Bacterial production and functional characterization of the Fab fragment of the murine IgG1/{lambda} monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics.
Protein Eng Des Sel. 2010 Feb 1. DOI: 10.1093/protein/gzp095
Oxidative stress modulates theophylline effects on steroid responsiveness.
Biochem. Biophys. Res. Commun. 2008 Dec 19; 377(3):797-802. Epub 2008 Oct 23. DOI: 10.1016/j.bbrc.2008.10.065
| Marwick JA | Wallis G | Meja K | Kuster B | Bouwmeester T | Chakravarty P | Fletcher D | Whittaker PA | Barnes PJ | Ito K | Adcock IM | Kirkham PA |
| Online reference |
Robust and sensitive iTRAQ quantification on an LTQ Orbitrap mass spectrometer.
Mol Cell Proteomics. 2008 Sep; 7(9):1702-13. Epub 2008 May 29. DOI: 10.1074/mcp.M800029-MCP200
Human Proteinpedia enables sharing of human protein data.
Nat Biotechnol. 2008 Feb; 26(2):164-7. DOI: 10.1038/nbt0208-164
| Mathivanan S | Ahmed M | Ahn NG | Alexandre H | Amanchy R | Andrews PC | Bader JS | Balgley BM | Bantscheff M | Bennett KL | Björling E | Blagoev B | Bose R | Brahmachari SK | Burlingame AS | Bustelo XR | Cagney G | Cantin GT | Cardasis HL | Celis JE | Chaerkady R | Chu F | Cole PA | Costello CE | Cotter RJ | Crockett D | DeLany JP | De Marzo AM | DeSouza LV | Deutsch EW | Dransfield E | Drewes G | Droit A | Dunn MJ | Elenitoba-Johnson K | Ewing RM | Van Eyk J | Faca V | Falkner J | Fang X | Fenselau C | Figeys D | Gagné P | Gelfi C | Gevaert K | Gimble JM | Gnad F | Goel R | Gromov P | Hanash SM | Hancock WS | Harsha HC | Hart G | Hays F | He F | Hebbar P | Helsens K | Hermeking H | Hide W | Hjernø K | Hochstrasser DF | Hofmann O | Horn DM | Hruban RH | Ibarrola N | James P | Jensen ON | Jensen PH | Jung P | Kandasamy K | Kheterpal I | Kikuno RF | Korf U | Körner R | Kuster B | Kwon MS | Lee HJ | Lee YJ | Lefevre M | Lehvaslaiho M | Lescuyer P | Levander F | Lim MS | Löbke C | Loo JA | Mann M | Martens L | Martinez-Heredia J | McComb M | McRedmond J | Mehrle A | Menon R | Miller CA | Mischak H | Mohan SS | Mohmood R | Molina H | Moran MF | Morgan JD | Moritz R | Morzel M | Muddiman DC | Nalli A | Navarro JD | Neubert TA | Ohara O | Oliva R | Omenn GS | Oyama M | Paik YK | Pennington K | Pepperkok R | Periaswamy B | Petricoin EF | Poirier GG | Prasad TS | Purvine SO | Rahiman BA | Ramachandran P | Ramachandra YL | Rice RH | Rick J | Ronnholm RH | Salonen J | Sanchez JC | Sayd T | Seshi B | Shankari K | Sheng SJ | Shetty V | Shivakumar K | Simpson RJ | Sirdeshmukh R | Siu KW | Smith JC | Smith RD | States DJ | Sugano S | Sullivan M | Superti-Furga G | Takatalo M | Thongboonkerd V | Trinidad JC | Uhlen M | Vandekerckhove J | Vasilescu J | Veenstra TD | Vidal-Taboada JM | Vihinen M | Wait R | Wang X | Wiemann S | Wu B | Xu T | Yates JR | Zhong J | Zhou M | Zhu Y | Zurbig P | Pandey A |
| Online reference |
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.
Nat Biotechnol. 2007 Sep; 25(9):1035-44. Epub 2007 Aug 26. DOI: 10.1038/nbt1328
| Bantscheff M | Eberhard D | Abraham Y | Bastuck S | Boesche M | Hobson S | Mathieson T | Perrin J | Raida M | Rau C | Reader V | Sweetman G | Bauer A | Bouwmeester T | Hopf C | Kruse U | Neubauer G | Ramsden N | Rick J | Kuster B | Drewes G |
| Online reference |
Quantitative mass spectrometry in proteomics: a critical review.
Anal. Bioanal. Chem. 2007 Oct; 389(4):1017-31. Epub 2007 Aug 1. DOI: 10.1007/s00216-007-1486-6
Computational prediction of proteotypic peptides for quantitative proteomics.
Nat Biotechnol. 2007 Jan; 25(1):125-31. Epub 2006 Dec 31. DOI: 10.1038/nbt1275
| Mallick P | Schirle M | Chen SS | Flory MR | Lee H | Martin D | Ranish J | Raught B | Schmitt R | Werner T | Kuster B | Aebersold R |
| Online reference |
Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.
Mol Cell Proteomics. 2006 Dec; 5(12):2211-27. Epub 2006 Sep 6. DOI: 10.1074/mcp.M600147-MCP200
| Angrand PO | Segura I | Völkel P | Ghidelli S | Terry R | Brajenovic M | Vintersten K | Klein R | Superti-Furga G | Drewes G | Kuster B | Bouwmeester T | Acker-Palmer A |
| Online reference |
Proteome survey reveals modularity of the yeast cell machinery.
Nature. 2006 Mar 30; 440(7084):631-6. Epub 2006 Jan 22. DOI: 10.1038/nature04532
| Gavin AC | Aloy P | Grandi P | Krause R | Boesche M | Marzioch M | Rau C | Jensen LJ | Bastuck S | Dümpelfeld B | Edelmann A | Heurtier MA | Hoffman V | Hoefert C | Klein K | Hudak M | Michon AM | Schelder M | Schirle M | Remor M | Rudi T | Hooper S | Bauer A | Bouwmeester T | Casari G | Drewes G | Neubauer G | Rick JM | Kuster B | Bork P | Russell RB | Superti-Furga G |
| Online reference |
Scoring proteomes with proteotypic peptide probes.
Nat Rev Mol Cell Biol. 2005 Jul; 6(7):577-83. DOI: 10.1038/nrm1683
Covalent cross-links between the gamma subunit (FXYD2) and alpha and beta subunits of Na,K-ATPase: modeling the alpha-gamma interaction.
J Biol Chem. 2005 May 6; 280(18):18291-301. Epub 2005 Mar 2. DOI: 10.1074/jbc.M500080200
A proteome-wide approach identifies sumoylated substrate proteins in yeast.
J Biol Chem. 2004 Oct 1; 279(40):41346-51. Epub 2004 Jul 30. DOI: 10.1074/jbc.M407950200
Phospho.ELM: a database of experimentally verified phosphorylation sites in eukaryotic proteins.
BMC Bioinformatics. 2004 Jun 22; 5:79. DOI: 10.1186/1471-2105-5-79
| Diella F | Cameron S | Gemünd C | Linding R | Via A | Kuster B | Sicheritz-Pontén T | Blom N | Gibson TJ |
| Online reference |
Femtomol sensitivity post-digest (18)O labeling for relative quantification of differential protein complex composition.
Rapid Commun Mass Spectrom. 2004; 18(8):869-76. DOI: 10.1002/rcm.1418
Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.
J Biol Chem. 2004 Mar 26; 279(13):12804-11. Epub 2003 Dec 15. DOI: 10.1074/jbc.M312171200
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
Nat Cell Biol. 2004 Feb; 6(2):97-105. Epub 2004 Jan 25. DOI: 10.1038/ncb1086
| Bouwmeester T | Bauch A | Ruffner H | Angrand PO | Bergamini G | Croughton K | Cruciat C | Eberhard D | Gagneur J | Ghidelli S | Hopf C | Huhse B | Mangano R | Michon AM | Schirle M | Schlegl J | Schwab M | Stein MA | Bauer A | Casari G | Drewes G | Gavin AC | Jackson DB | Joberty G | Neubauer G | Rick J | Kuster B | Superti-Furga G |
| Online reference |
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes.
Mol Cell. 2003 Dec; 12(6):1489-98. DOI: 0.1016/S1097-2765(03)00478-7
Profiling core proteomes of human cell lines by one-dimensional PAGE and liquid chromatography-tandem mass spectrometry.
Mol Cell Proteomics. 2003 Dec; 2(12):1297-305. Epub 2003 Oct 6. DOI: 10.1074/mcp.M300087-MCP200
ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins.
Nucleic Acids Res. 2003 Jul 1; 31(13):3625-30. DOI:10.1093/nar/gkg545
| Puntervoll P | Linding R | Gemünd C | Chabanis-Davidson S | Mattingsdal M | Cameron S | Martin DM | Ausiello G | Brannetti B | Costantini A | Ferrè F | Maselli V | Via A | Cesareni G | Diella F | Superti-Furga G | Wyrwicz L | Ramu C | McGuigan C | Gudavalli R | Letunic I | Bork P | Rychlewski L | Kuster B | Helmer-Citterich M | Hunter WN | Aasland R | Gibson TJ |
| Online reference |
Affinity purification-mass spectrometry. Powerful tools for the characterization of protein complexes.
Eur J Biochem. 2003 Feb; 270(4):570-8. DOI:10.1046/j.1432-1033.2003.03428.x
Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins.
Nat Cell Biol. 2003 Jan; 5(1):21-7. DOI:10.1038/ncb893
An improved two-step calibration method for matrix-assisted laser desorption/ionization time-of-flight mass spectra for proteomics.
Rapid Commun Mass Spectrom. 2002; 16(19):1892-5. DOI:10.1002/jms.416
90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors.
Mol Cell. 2002 Jul; 10(1):105-15. DOI:10.1016/S1097-2765(02)00579-8
| Grandi P | Rybin V | Bassler J | Petfalski E | Strauss D | Marzioch M | Schäfer T | Kuster B | Tschochner H | Tollervey D | Gavin AC | Hurt E |
| Online reference |
A transmembrane tight junction protein selectively expressed on endothelial cells and platelets.
J Biol Chem. 2002 May 3; 277(18):16294-303. Epub 2002 Feb 14. DOI:10.1074/jbc.M111999200
| Nasdala I | Wolburg-Buchholz K | Wolburg H | Kuhn A | Ebnet K | Brachtendorf G | Samulowitz U | Kuster B | Engelhardt B | Vestweber D | Butz S |
| Online reference |
Tyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathway.
J Biol Chem. 2002 Jan 11; 277(2):1031-9. Epub 2001 Oct 30. DOI:10.1074/jbc.M109992200
Functional organization of the yeast proteome by systematic analysis of protein complexes.
Nature. 2002 Jan 10; 415(6868):141-7. DOI:10.1038/415141a
| Gavin AC | Bösche M | Krause R | Grandi P | Marzioch M | Bauer A | Schultz J | Rick JM | Michon AM | Cruciat CM | Remor M | Höfert C | Schelder M | Brajenovic M | Ruffner H | Merino A | Klein K | Hudak M | Dickson D | Rudi T | Gnau V | Bauch A | Bastuck S | Huhse B | Leutwein C | Heurtier MA | Copley RR | Edelmann A | Querfurth E | Rybin V | Drewes G | Raida M | Bouwmeester T | Bork P | Seraphin B | Kuster B | Neubauer G | Superti-Furga G |
| Online reference |
Mass spectrometry allows direct identification of proteins in large genomes.
Proteomics. 2001 May; 1(5):641-50.DOI:10.1002/1615-9861(200104)1:5<641::AID-PROT641>3.0.CO;2-R
Glycosylation analysis of gel-separated proteins.
Proteomics. 2001 Feb; 1(2):350-61.DOI:10.1002/1615-9861(200102)1:2<350::AID-PROT350>3.0.CO;2-7
Quadrupole time-of-flight versus triple-quadrupole mass spectrometry for the determination of phosphopeptides by precursor ion scanning.
J Mass Spectrom. 2001 Jul; 36(7):782-90. DOI:10.1002/jms.174
Detection of tyrosine phosphorylated peptides by precursor ion scanning quadrupole TOF mass spectrometry in positive ion mode.
Anal Chem. 2001 Apr 1; 73(7):1440-8.DOI:10.1021/ac001318c
Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.
EMBO J. 2000 Dec 1; 19(23):6569-81.DOI:10.1093/emboj/19.23.6569
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres.
Nat Genet. 2000 Jul; 25(3):347-52.DOI:10.1038/77139
Composition of N-linked carbohydrates from ovalbumin and co-purified glycoproteins.
J Am Soc Mass Spectrom. 2000 Jun; 11(6):564-71. DOI:10.1016/S1044-0305(00)00122-7
A new variant of the gamma subunit of renal Na,K-ATPase. Identification by mass spectrometry, antibody binding, and expression in cultured cells.
J Biol Chem. 2000 Jun 16; 275(24):18441-6. DOI:10.1074/jbc.M001411200
Characterisation of tissue-specific oligosaccharides from rat brain and kidney membrane preparations enriched in Na+,K+-ATPase.
Glycoconj J. 1999 Aug; 16(8):437-56. DOI:10.1023/A:1007078511110
Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.
Biochemistry. 1999 Oct 19; 38(42):13937-50. DOI:110.1021/bi991162e
| Rudd PM | Mattu TS | Masure S | Bratt T | Van den Steen PE | Wormald MR | Kuster B | Harvey DJ | Borregaard N | Van Damme J | Dwek RA | Opdenakker G |
| Online reference |
18O-labeling of N-glycosylation sites to improve the identification of gel-separated glycoproteins using peptide mass mapping and database searching.
Anal Chem. 1999 Apr 1; 71(7):1431-40. DOI:10.1021/ac981012u
Oligosaccharides of recombinant mouse gelatinase B variants.
Biochim Biophys Acta. 1998 Nov 27; 1425(3):587-98. DOI:10.1016/S0304-4165(98)00113-5
| Van den Steen P | Rudd PM | Proost P | Martens E | Paemen L | Kuster B | van Damme J | Dwek RA | Opdenakker G |
| Online reference |
Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulphate-polyacrylamide electrophoresis gels: application to species-specific glycosylation of alpha1-acid glycoprotein.
Electrophoresis. 1998 Aug; 19(11):1950-9. DOI:-
Identifying proteins and post-translational modifications by mass spectrometry.
Curr Opin Struct Biol. 1998 Jun; 8(3):393-400. DOI:10.1016/S0959-440X(98)80075-4
Partially glucose-capped oligosaccharides are found on the hemoglobins of the deep-sea tube worm Riftia pachyptila.
Glycobiology. 1998 Jul; 8(7):663-73. DOI:-
Perspectives in the glycosciences--matrix-assisted laser desorption/ionization (MALDI) mass spectrometry of carbohydrates.
Glycoconj J. 1998 Apr;15(4):333-8. DOI:10.1023/A:1006913616252
Sequencing of N-linked oligosaccharides directly from protein gels: in-gel deglycosylation followed by matrix-assisted laser desorption/ionization mass spectrometry and normal-phase high-performance liquid chromatography.
Anal Biochem. 1997 Jul 15; 250(1):82-101. DOI:10.1006/abio.1997.2199
Oligosaccharide sequencing technology.
Nature. 1997 Jul 10; 388(6638):205-7. DOI:10.1038/40677
Ammonium containing buffers should be avoided during enzymatic release of glycans from glycoproteins when followed by reducing terminal derivatization.
Glycobiology. 1997 Mar; 7(2):vii-ix.DOI:10.1093/glycob/7.2.161-a
Rapid approach for sequencing neutral oligosaccharides by exoglycosidase digestion and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
J Mass Spectrom. 1996 Oct; 31(10):1131-40.DOI:10.1002/(SICI)1096-9888(199610)31:10<1131::AID-JMS401>3.0.CO;2-R
Identification of oligosaccharides by matrix-assisted laser desorption ionization and electrospray MS.
Biochem Soc Trans. 1996 Aug; 24(3):905-12.DOI:-
Effect of the reducing-terminal substituents on the high energy collision-induced dissociation matrix-assisted laser desorption/ionization mass spectra of oligosaccharides.
Rapid Commun Mass Spectrom. 1996; 10(13):1645-51.DOI:10.1002/(SICI)1097-0231(199610)10:13<1645::AID-RCM664>3.0.CO;2-N
Comparison of fragmentation modes for the structural determination of complex oligosaccharides ionized by matrix-assisted laser desorption/ionization mass spectrometry.
Rapid Commun Mass Spectrom. 1995;9(15):1556-61.DOI:10.1002/rcm.1290091517
back
Chair of Proteomics and Bioanalytics
NEWS
15 April 2012
Glyco-TMTs -- novel tools for glyco-proteomics
more
13 October 2011
TUM and Oxford scientists team up for the identification of novel drug targets and biomarkers in head & neck cancer.
more
25 April 2011
Chair of proteomics acquires 2.5 M€ large scale equipment grant for interdisciplinary research
more
29 March 2011
New O-GlcNAc research paper in JASMS
more
26 November 2010
Life science teaching award for Bernhard Kuster
more
News archive
