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09 November 2010

New research paper in Molecular and Cellular Proteomics: Confident phosphorylation site localization using the Mascot Delta Score

Large scale phosphorylation analysis is more and more getting into focus of proteomic research. While it is now possible to identify thousands of phosphorylated peptides in a biological system, confident site localization remains challenging. Here we validate the Mascot Delta Score (MD score) as a simple method that achieves similar sensitivity and specificity for phosphosite localization as the published Ascore which is mainly used in conjunction with Sequest.

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26 October 2010

Harald Marx wins PhD scholarship of the Universitaet Bayern

Harald Marx has been awarded the prestigious PhD elite scholarship of the Universitaet Bayern e.V..

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09 July 2010

New article in Nature Biotechnology: Proteomics – A Pragmatic Perspective

Today, we announce the publication of a new article in Nature Biotechnology. It is entitled Proteomics - A Pragmatic Perspective and was compiled by Parag Mallick of the University of California and Bernhard Kuster of the Technische Universität München.

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01 July 2010

Welcome Stefan Maier, new joint PhD student of the TUM and HZM

Today, we welcome Stefan Maier, a new PhD student jointly supervised by Bernhard Kuster (Technische Universität München) and Axel Walch (Helmholz Zentrum München).

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01 April 2010

We welcome Dr Estela del Castillo, new Alexander von Humboldt Fellow from Spain

At the beginning of April, Dr Estela del Castillo joined the research team at the Chair of Proteomics and Bioanalytics of the TUM.

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16 March 2010

Cross-species network inference

Cross-species meta-analyses of microarray data usually require prior affiliation of genes based on orthology information that often relies on sequence similarity. We present an algorithm merging microarray datasets on the basis of co-expression alone, without any requirement for orthology information to affiliate genes.

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10 March 2010

New research paper

Today, we announce the publication of a collaborative reseach paper entiteled: Bacterial production and functional characterization of the Fab fragment of the murine IgG1/{lambda} monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics.

Friedrich L, Stangl S, Hahne H, Küster B, Köhler P, Multhoff G, Skerra A.

Protein Eng Des Sel. 2010 Feb 1. [Epub ahead of print]. PMID: 20123884

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17 August 2009

New giant equipment improves proteomics research at the Technische Universität München

What do such diverse fields as nutrition physiology, systems biology, and bioanalytics have in common? All of them explore the protein building blocks of life by mass spectrometry. At the Chair of Proteomics and Bioanalytics of the Technische Universität München (TUM) two mass spectrometers worth about 800,000 Euro were recently put into operation. These new appliances will benefit many departments: They will be used interdisciplinary and set the starting point of a TUM-wide technology center for proteomics.

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05 February 2010

Proteomics former exams online

The former exams for the Proteomics lecture are online and can be downloaded in the scripts section.

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01 February 2009

GDCH-Course Proteome-Analytics

23 November - 26 November 2009, Chair of Bioanalytics

The course should qualify the participants, to perform autonomous proteome analysis via two-dimensional (2D) electrophoresis (including sample preparation and computer-aided image evaluation) and mass spectrometry (MALDI-TOF-MS, ESI-MS/MS, protein database search).

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31 January 2009

Award of PhD scholarship

We are very happy to announce that Hannes Hahne has been awarded a prestigious PhD scholarship of the Studienstiftung des Deutschen Volkes. Hannes will perform research towards the identification of post-translational protein modifications that play a role in cellular signal transduction pathways.

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19 January 2009

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Cancer Research: 900 000 Euro for Bioanalytics group at the TU München

In search for new therapeutic agents for cancer therapy, the Technische Universität München (TUM), the state of Bavaria and the Deutsche Forschungsgemeinschaft (DFG) provided the Interdisciplinary Protein Analysis Group at the TUM with a state-of-the-art mass spectrometer worth some 900,000 Euro. The mass spectrometer was deployed at the beginning of the year and will enable the interdisciplinary research team around Prof. Bernhard Küster in Weihenstephan to conduct applied as well as fundamental cancer research.

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Chair of Proteomics and Bioanalytics

Chair of Proteomics and Bioanalytics

NEWS

15 April 2012

Glyco-TMTs -- novel tools for glyco-proteomics

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13 October 2011

TUM and Oxford scientists team up for the identification of novel drug targets and biomarkers in head & neck cancer.

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25 April 2011

Chair of proteomics acquires 2.5 M€ large scale equipment grant for interdisciplinary research

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29 March 2011

New O-GlcNAc research paper in JASMS

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26 November 2010

Life science teaching award for Bernhard Kuster

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